The Science of Sleep: What It Is, How It Works, and Why It Matters

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Science of sleepWe often hear that humans spend one third of their lives sleeping—and most of us would up that fraction if we could. Whether we’re curling up for a brief lunchtime catnap, catching a doze on a sunny afternoon, or clocking our solid eight hours at night, sleeping is normally a reliable way to rest our heads and recharge our minds. And our bodies demand it: without sufficient sleep, we experience changes in mood, memory loss, and difficulty concentrating. Symptoms of sleep deprivation can be severe, and we know that sleep is essential for restoring and rejuvenating muscles, tissue, and energy. And yet, although science is making remarkable inroads into the workings and functions of sleep, many aspects still remain a mystery.
In The Science of Sleep, sleep expert Wallace B. Mendelson explains the elements of human sleep states and explores the variety of sleep disorders afflicting thousands of people worldwide. Mendelson lays out the various treatments that are available today and provides a helpful guide for one of life’s most important activities. By offering the first scientific yet accessible account of sleep science, Mendelson allows readers to assess their personal relationships with sleep and craft their own individual approaches to a comfortable and effective night’s rest.
Addressing one of the major public health issues of the day with cutting-edge research and empathetic understanding, The Science of Sleep is the definitive illustrated reference guide to sleep science.
Praise for The Science of Sleep:
“Not only does this book remind us why we need sleep but it also tells us what happens if we don’t get enough of it.” – Euro Scientist
“Dr Mendelson provides a readable, engaging, and clearly written work concerning sleep science and medicine. His ability to explain complexities in a manner that communicates essential characteristics is truly artful. And speaking of art, the illustrations and layout make this book a joy to open and begin reading or skimming on any page. For anyone serious about sleep science, this book should sit prominently on a nearby bookshelf, assuming it ever gets off your desk.” – Max Hirshkowitz, PhD, Sleep Specialist 
Excerpt from The Science of Sleep:
Sleep means different things to different people, and indeed its meaning differs in the same person at various times. I remember, for instance, as a little boy, going to bed anticipating the presents awaiting me on Christmas morning, and thinking that since I would soon be asleep, the time would seem to pass in an instant. Then the presents would be mine. Not surprisingly, that sort of thinking led to the opposite, a long period of unhappy wakefulness. The opposite can occur as well, as in the song “The Green Green Grass of Home”, in which sleep is a time of escape into happy memories, in contrast to the very unfortunate events awaiting the sleeper in the morning. For others, sleep can become a kind of testing ground: a person who prides herself on always being the best at whatever she does can view good sleep as a challenge, something she has to work at—the result, paradoxically, being poor sleep. It can also be a time of anxiety. People for whom it is important to feel in control of things can find it worrisome to have a period each night in which they seem more vulnerable and not in charge.  For others, sleep can be a time of getting a glimpse of the “real” world; I have had patients who say that their dream experiences during sleep seem so much more real and meaningful than what they awaken to in the morning.
Sleep is also inextricably tied to the notion of restoration. After a good night’s sleep a healthy person awakens with a sense of vitality, of readiness to face the new day. As we will discuss later, no one is certain what this entails physiologically—it is not just a simple matter of increasing metabolic energy stores—but its presence (or absence) plays a role in what we think about sleep.  Related to this is the notion of sleep as a pleasurable experience, something to look forward to. Sadly, for many people the opposite is true. The genesis of this is not always clear. Some think that a lifelong feeling that sleep is an unhappy time is a derivative of childhood experiences, in which the more typical learning association of sleeping with pleasure did not take place. Others view this as a disorder of the amount of l brain chemicals that normally bring on sleep. Another view is that it may result from habits in which bedtime is used for behaviors incompatible with sleep, such as worrying and planning tomorrow’s battles.
Sleep is also inextricably tied to the environment in which we live, in a world of alternating day and night. Our bodies have developed elaborate mechanisms to help time our waking and sleep to be in conjunction with light and darkness. Sometimes this timing can go astray, either due to behaviors such as engaging in shift work or flying long distances, or due to inherent problems of the body clock. These in turn can lead to difficulties with sleeping, or at least with sleeping during the traditional hours allocated for it.
Sleep can also be a kind of social behavior, inside the species, or across species (for instance when sleeping with a pet). We often use the euphemism of sleeping together to refer to another kind of activity that can take place in bed, but this kind of delicate phraseology can obscure another aspect, which is that repetitive sharing of the sleep experience may play a role in a couple bonding together.
There is also a sense that sleep is important to health, both physical and mental. Sleep which is curtailed or disrupted can lead, for instance, to a predilection to diabetes and related disorders. It seems to be important for the formation of long-term memories. This suggests, for instance, the futility of students doing “all nighters” of studying. It turns out that getting a good night’s sleep may be the most helpful thing in preparation for  an exam in the morning.  One of the great believers in a good night’s sleep, incidentally, was Alexander the Great.  In 331 BC, before the crucial battle in which he overwhelmed a vastly larger Persian army on their own territory, he slept so deeply that his officers became worried and had to awaken him.  He got up, put on his armor, and went on to an outstanding victory which set the stage for conquering an empire.
In this book we will present the scientific understanding of sleep, beginning by describing its basic processes and how to measure them. It will be seen that sleep results from the careful orchestration of a variety of physiologic processes. As in any complex mechanism, sometimes things go awry, in this case resulting in clinical sleep disorders which are experienced as insomnia, excessive sleepiness or undesirable behaviors during sleep. We will describe some of these disorders, and some of the treatments that are available. This information is not a substitute for medical evaluation. If you think you may have a sleep disorder, you should consult your doctor for evaluation and possible referral to a sleep disorders center. It is hoped that armed with the information provided here, you will be better able to understand and discuss what is happening, and to make more informed choices in conjunction with your doctor.
Just as sleep is a universal human behavior, so is human curiosity and the desire to know more about ourselves. A number of men and women devoted themselves to learn more about sleep, long before sleep studies became an established scientific discipline. They came from a variety of unlikely backgrounds—a WW I cavalryman, and a fighter pilot, for example. One was looking for something entirely else, the basis of a supposed “psychic energy” which might let people communicate across long distances, and ended instead with the groundbreaking discovery of the human electroencephalogram. Another was a doctor faced with treating patients in a worldwide epidemic of encephalitis, who recognized a pattern to the parts of the affected brains—and learned from it the basic structures making it possible for us to be awake or asleep. Another had made his fame developing a method to precisely measure the speed of projectiles for the Army, but his curiosity led him to measurements of many other kinds of things, including electrical waveforms during the human sleep stages. If you, the reader, have picked up this book, it sounds like you, too, have curiosity about how things work, and it is my hope that here you will learn more about how we wake and sleep.
Wallace MendelsonAbout the Author:
Wallace B. Mendelson, M.D., has more than forty years of experience in sleep research and clinical care – as a Professor of Psychiatry and Clinical Pharmacology (ret), former director of the Sleep Research Laboratory at the University of Chicago, and past president of the Sleep Research Society. He has written five books and numerous scientific papers on sleep disorders. He has also been the recipient of various honors including a special award for excellence in sleep and psychiatry from the National Sleep Foundation in 2010. To learn more, go to https://www.zhibit.org/WallaceMendelson

 

 

Danko Antolovic’s Latest Book Shines Light on Some of the Questions Facing Modern Science

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whither science book coverFebruary 25, 2016 (Bloomington, IN) – Scientist and intellectual essayist Danko Antolovic announced today that his latest book, Whither Science? is now available for purchase on Smashwords, Barnes & Noble, and iBooks.  Whither Science? is a series of essays that explore some of the questions facing modern science.
“In Whither Science?, we look at the history of science, question its practices and examine its potential,” says Danko Antolovic. “We examine the strengths and weaknesses of the scientific method, and we seek to understand the worldview that follows from it. Lastly, and most importantly, we inquire about the future of science and about the problems that science urgently needs to solve.”
Science and the scientific method have matured into a global endeavor, which influences all of contemporary life, and like other great human endeavors, science has its historical origins and intellectual foundations. It has a set of accepted principles, as well as current practices that do not always coincide with the professed principles, and it has choices to make for the future.
Whither Science? looks into the fundamental questions about the purposes, practices and future of science. These questions need to be asked because both scientists and the broader public, that is, all who benefit from science, should try to understand the social, historical and material consequences of science’s ubiquitous presence.
This book is written in non-technical language, and is intended to be easily accessible to general readers who are interested in science and its broader implications. It will also be of interest to scientists who seek to explore the intellectual context of their discipline.
Danko Antolovic is a scientist and technologist whose professional activities and publications have included research in quantum chemistry and computational modeling of molecules, research in solar energy for space applications, design of systems for image analysis and robotic vision, and development of wireless communication technology. He received his doctorate and master’s degree in Chemistry from Johns Hopkins University, and a master’s degree in Computer Science from Indiana University. He currently resides in Bloomington, IN.
For further information, to request a review copy, or to set up an interview or appearance by Danko Antolovic, please contact Kelsey McBride at Book Publicity Services at bookpublicityservices@gmail.com or 805.807.9027.
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Whither Science? by Danko Antolovic

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whither science book cover
Whither Science? by Danko Antolovic is a series of essays that explore some of the questions facing modern science.
“In Whither Science?, we look at the history of science, question its practices and examine its potential,” says Danko Antolovic. “We examine the strengths and weaknesses of the scientific method, and we seek to understand the worldview that follows from it. Lastly, and most importantly, we inquire about the future of science and about the problems that science urgently needs to solve.”
Science and the scientific method have matured into a global endeavor, which influences all of contemporary life, and like other great human endeavors, science has its historical origins and intellectual foundations. It has a set of accepted principles, as well as current practices that do not always coincide with the professed principles, and it has choices to make for the future.
Whither Science? looks into the fundamental questions about the purposes, practices and future of science. These questions need to be asked because both scientists and the broader public, that is, all who benefit from science, should try to understand the social, historical and material consequences of science’s ubiquitous presence.
This book is written in non-technical language, and is intended to be easily accessible to general readers who are interested in science and its broader implications. It will also be of interest to scientists who seek to explore the intellectual context of their discipline.

 

Excerpt from Whither Science?:
The Age of Heroes
Foundational stories of the origins of peoples and cultures always exalt the past in order to validate the present, but we know that the here-and-now never quite measures up to the grand mythical past from which it supposedly descended. Heroic bygone days always give way to a mundane present, and not even the greatest historic rulers of ancient Greece had quite the stature of the legendary kings of the house of Atreus, or of Achilles and Odysseus, Homeric heroes of divine lineage. The latter heroes, for all their courage and wile, were in turn not the equals of their predecessors, the mythical gods who, in the beginning, shaped the world in blood-drenched acts of creation.
Our contemporary techno-scientific culture, which is close to being the global culture, has no foundational myth written in a great epic and chanted down the generations, but it does have a popularly accepted foundational narrative, which is retold in countless books on popular science, and which aims to explain science’s origins and validate its purpose. In this essay, we will briefly relate this narrative, and we will examine its transition into present-day science, a contemporary human endeavor for which the narrative still functions as the story of origin.
At the risk of being somewhat Eurocentric, by science we mean a systematic and uncompromising application of rational empirical inquiry to the material world. Of course, empirical inquiry is as old as the human kind, but its transformation into a fundamental outlook on the world, that is into “science,” took place in the 16th and  17th century Europe. Men who stand as symbols of that awakening are mainly the early astronomers: Nicolaus Copernicus, Tycho Brahe, Giordano Bruno, Galileo Galilei; in popular imagination they live on as Promethean figures who defied authority and brought the gift of light to humanity, and some of them, like Prometheus himself, did so at great personal cost.
European Enlightenment of the 17-18th century, and the Industrial Revolution, stretching through 19th century, is the Age of Heroes of classical science. This is the time of larger than life figures, “fathers” of scientific fields: Newton (mechanics and calculus), Boyle and Lavoisier (chemistry), Kelvin (thermodynamics), Darwin (evolution), Faraday (electromagnetism); mathematicians Leibniz, Euler and Gauss also belong here. And so on: our purpose is not to produce a full list of credits, but to sketch out the popular narrative, incomplete as it inevitably is. The later part of that period, the 18th and 19th century, could also be called more prosaically the Age of Progress: many of the scientific names and discoveries from that time enjoy little popular recognition, but that was the period in which the breakthroughs of the heroic age matured into a way of life and formed the foundations for today’s technology-based society.
Early 20th century saw another, late heroic period, belonging to atomic physics and the theory of relativity; in popular imagination, this period in science’s history is represented by the slightly idiosyncratic visage of Albert Einstein, and by the mushroom cloud. The foundational narrative of science, as we outline it here, ends with the Second World War and the development of the atom bomb. This is the time when heroic ages come to a close, and science comes under the sway of earthly rulers, of history, and of politics.
Now, it is certainly true that scientific progress provided useful help to state power well before the atom bomb, and in any case heroic ages are always more allegorical than factual. But the development of the nuclear weapon is a historical marker of the changed status of science in society, since the magnitude of the bomb’s power made it clear that the very survival of nation states would depend on the national prowess in that application of empirical inquiry that we call science. Science would from then on be co- opted, managed and circumscribed by political powers.
Intellectual status of the scientist changed at the same time: he would no longer be the autonomous, intellectually esteemed and perhaps marginally irrelevant pursuer of esoteric quests, and would become society’s artisan, maker of useful things. Again, history is gradual, but two historical episodes serve as useful markers of that change:
Toward the end of the Manhattan Project, a sizable group of scientists who were involved in the development of the bomb, led by Leo Szilard, petitioned the United States government for restraint in its use. They were summarily ignored, and the bombing of population centers in Japan went ahead. The shiny new weapon that they had provided was not theirs to dispose of or haggle about – they were the craftsmen, not the decision makers.
After the war, Julius Robert Oppenheimer, a highly prominent scientific figure in the Manhattan Project, was accused of “communist sympathies,” investigated, and disgraced. Historians may argue about the merits of the charges, but this certainly was a cold- hearted destruction of a man who had contributed much to the technological basis of America’s nascent superpower status. Whether intentionally or otherwise, the Oppenheimer episode made it clear who was dispensable and who was not, in the emerging techno-scientific order.
Ironically perhaps, the fate of Oppenheimer wasn’t even a novel one. Long before him, mythical inventor Daedalus also discovered that skill and mastery over matter did not guarantee power, or even protection, in the world of men: disregarding his good service, the story tells us, Minos of Crete imprisoned and abused him in a fit of anger. He, Daedalus, was an artisan, maker of useful things; Minos was king.
Significance of the foundational narrative that we outlined above reaches beyond popular science classes. Today, the practitioner of science is almost without exception an employee of a larger corporate entity (a university or a company) or of a national government. He is hemmed in by the tangible constraints of his terms of employment and funding, and by the less tangible ones of departmental, institutional and funding politics. He labors in a crowded field, in which there are increasingly fewer stones left unturned, and he climbs the ladder of corporate seniority until he retires.
Since scientific development is fundamentally important to the well-being of modern societies, it is easy to see the benefits of exalting this decidedly un-adventurous walk of life with the help of a heroic foundation story. In the eyes of the supporting public, and in those of prospective practitioners, present-day science is the heir and descendant of the heroic achievements that dispelled the darkness of superstition, changed our image of the universe, and wonder-worked what we today know as the industrial world. And so it is, but we should examine the heir on his own merits.
Incidentally, science proper isn’t the only one claiming heroic validation. Industry based on science is eager to convince us that the past isn’t really over: heroic times are still with us, we are told that we now live in the “digital” age, and its tycoons are quick to claim the title of “genius,” closest modern equivalent of demigod. We should feel uneasy about these latter-day claims to heroic-age continuity: when king Alexander of Macedon elevated himself to divine status, that was an embarrassing overreach of a great man; when emperor Caligula did the same, it was the delusion of a fool.

 

Danko Antolovic About the Author
Danko Antolovic is a scientist and technologist whose professional activities and publications have included research in quantum chemistry and computational modeling of molecules, research in solar energy for space applications, design of systems for image analysis and robotic vision, and development of wireless communication technology. He received his doctorate and master’s degree in Chemistry from Johns Hopkins University, and a master’s degree in Computer Science from Indiana University.
Danko is the author of a monograph on wireless technology, “Radiolocation in Ubiquitous Wireless Communication” published by Springer in 2010. In addition to Whither Science? his non-technical writings include a recently published essay on the philosopher René Descartes, “Descartes’ Menagerie of Demons,” and an upcoming novella based on the Greek myths about the legendary inventor Daedalus, in which Daedalus retells the myths as his own life story.
Danko currently resides in Bloomington, IN. In his free time, he enjoys reading folk tales, fantastic and slightly surreal stories, and occasional science fiction. Readers can connect with him on Facebook, Twitter, and Goodreads.
For further information, to request a review copy, or to set up an interview or appearance by Danko Antolovic, please contact Kelsey McBride at Book Publicity Services at Kelsey@BookPublicityServices.com or 805.807.9027.